Lock please.
What ingredients are you trying to use, and have you checked the boxes beneath them to combine them?
It would be helpful if you told us what you were tiring to use as ingredients. @ Fyreheart [edit] Beaten, even refreshed before posting too.
Dark Light Potion + 50HP Healing Potion according to EVERY guide I've looked at. I managed to make the Essence of Plutonium without any problem so I don't know what's wrong.
Ah! It suddenly...took for some reason. Weird. Ah well. Thanks anyway, guys.
You created a Vibrating Nucleus Gel!
Not sure what's going wrong there either.
It worked for me :